Collaborative Team Led by Drs. Jason Franz and Brian Pietrosimone Secures $3M NIH Grant to Study Cartilage Degeneration and Knee OA
An interdisciplinary team of Thurston Arthritis Research Center members spanning biomedical engineering, exercise and sports science, biostatistics has received a new 5-year, $3M R01 Grant from the National Institutes of Health titled “Discovering the Mechanisms Linking Gait to Osteoarthritis Onset and Progression.”
The project is led by co-principal investigators Jason Franz, associate professor of biomedical engineering, and Brian Pietrosimone, professor in exercise and sport science. Collaborators include Brian Diekman and David Lalush, associate professors of biomedical engineering, Todd Schwartz, professor of biostatistics, and Lara Longobardi, associate professor of medicine.
The team will investigate how abnormal knee joint loading during walking affects the mechanical, biophysical, and biological properties of tibiofemoral articular cartilage in those at risk for knee osteoarthritis. They stated that establishing this pathway is crucial for advancing precision gait retraining to prevent knee osteoarthritis.
This story was first written and published on the Joint Department of Biomedical Engineering’s website.
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